Other Clinical Studies

Related to Cerebral Palsy

To date, Cure CP funds the studies listed under Studies We Support. There are other clinical trials for patients with cerebral palsy. If you are interested in any of the ongoing trials listed below, please visit www.clinicaltrials.gov


Safety and Effectiveness of Cord Blood Stem Cell Infusion for the Treatment of Cerebral Palsy in Children.

ClinicalTrials.gov Identifier: NCT01072370

This study is currently recruiting participants.

Verified August 2016 by Augusta University

Sponsor: Augusta University

Information provided by (Responsible Party): James E. Carroll, Georgia Regents University

First received: February 16, 2010

Last updated: August 9, 2016

Last verified: August 2016

The purpose of this study is to test the safety and effectiveness of a cord blood infusion in children who have motor disability due to cerebral palsy (CP). The subjects will be children whose parents have saved their infant’s cord blood, who have non-progressive motor disability, and whose parents intend to have a cord blood infusion.

Assessment of the Safety of Allogeneic Umbilical Cord Blood Infusions in Children With Cerebral Palsy

ClinicalTrials.gov Identifier: NCT02599207

Sponsor: Joanne Kurtzberg, MD

Information provided by (Responsible Party): Joanne Kurtzberg, MD, Duke University Medical Center

Last received: November 2, 2015

Last updated: July 27, 2016

Last verified: July 2016

This study is a single site, phase I, prospective study of the safety of intravenous sibling cord blood infusion in 15 children ages 1-6 years with Cerebral Palsy (CP). All subjects will be treated with sibling cord blood cells. The first six will receive cord blood cells from an HLA-matched sibling. The following nine subjects will receive cord blood cells from an HLA-mismatched (≥3/6 match) or matched sibling. The duration of study participation will be six months from the time of the cord blood infusion.

Robotic-assisted Therapy to Improve Manual Dexterity in Children With Cerebral Palsy

ClinicalTrials.gov Identifier: NCT02923167

This study is not yet open for participant recruitment.

Verified October 2016 by Spaulding Rehabilitation Hospital

Sponsor: Spaulding Rehabilitation Hospital

Information provided by (Responsible Party): Paolo Bonato, Spaulding Rehabilitation Hospital

First received:
September 30, 2016

Last updated: October 3, 2016

Last verified: October 2016

This is an intervention study including a baseline data collection, 6 weeks of a training intervention with robotic-assisted manual training, a post-intervention data collection, and a 4 weeks post-intervention follow-up data collection. The study will be conducted in the Motion Analysis Laboratory at Spaulding Rehabilitation Hospital, Boston, MA.This study aims to assess the effectiveness of a robot-assisted training on hand function and quality of life in children with cerebral palsy. Additionally, the investigators will study the relationship between muscle synergies and the outcomes of robot-assisted training.

G-CSF and Autologous Cord Blood Infusion in Cerebral Palsy

ClinicalTrials.gov Identifier: NCT02866331

This study is currently recruiting participants.

Verified August 2016 by Hanyang University Seoul Hospital

Sponsor: Hanyang University Seoul Hospital

Collaborator: Ministry of Health & Welfare, Korea

Information provided by (Responsible Party): Young-Ho Lee, Hanyang University Seoul Hospital

First received: July 26, 2016

Last updated: August 10, 2016

Last verified: August 2016

This study is performed to reveal the safety and feasibility of combination therapy with autologous cord blood mononuclear cells (CB) and G-CSF as well as repeated administration of G-CSF for children with cerebral palsy. The evaluation tools are as follows: (1) Developmental tests (DDST, PEDI, GMFM, GMFCS, MACS, QUEST), (2) Neurocognitive function test (WPPSI-IV), (3) Brain MRI-DTI, (4) Peripheral blood CD34+ cell counts, (5) Neurotrophic factors/anti-inflammatory cytokines.

Robotic Rehabilitation of Cerebral Palsy

ClinicalTrials.gov Identifier: NCT02359799

This study is currently recruiting participants.

Verified February 2015 by Rehabilitation Institute of Chicago

Sponsor: Rehabilitation Institute of Chicago

Collaborator: U.S. Department of Education

Information provided by (Responsible Party): Li-Qun Zhang, Rehabilitation Institute of Chicago

First received: January 26, 2015

Last updated: February 4, 2015

Last verified: February 2015

The purpose of this study is to investigate the effectiveness of home-based and lab-based stretching and active movement rehabilitation in reducing joint impairments in cerebral palsy using a portable rehabilitation robot. Children with spastic cerebral palsy and ankle impairments are divided randomly into two groups, participating in robot-guided passive and active movement training in a research lab setting (lab group) or in home setting (home group).

Cell Therapy as Treatment for Cerebral Palsy

ClinicalTrials.gov Identifier: NCT02241395

This study is currently recruiting participants. (See Contacts and Locations)

Verified September 2016 by Neurogen Brain and Spine Institute

Sponsor: Neurogen Brain and Spine Institute

Information provided by (Responsible Party): Neurogen Brain and Spine Institute

First received: September 12, 2014

Last updated: September 23, 2016

Last verified: September 2016

The purpose of this study was to study the effect of autologous bone marrow mononuclear cells on common symptoms of cerebral palsy patients.

Botulinum Toxin-A as a Treatment for Chronic Muscle-Related Pain in Adults With Spastic Cerebral Palsy: a Randomized Controlled Trial (BATCP)

ClinicalTrials.gov Identifier: NCT02434549

This study is currently recruiting participants.

Verified August 2016 by Karolinska Institutet

Sponsor: Kristina Tedroff

Collaborators: Department of Rehabilitation Medicine, Danderyd Hospital AB., Karolinska Trial Alliance, Karolinska University Hospital Huddinge.

Information provided by (Responsible Party): Kristina Tedroff, Karolinska Institutet

First received: April 30, 2015

Last updated: August 30, 2016

Last verified: August 2016

The purpose of this double-blinded, placebo-controlled study is to test if treatment with Botulinum toxin-A is effective in reducing chronic muscle-related pain in adults with spastic cerebral palsy.

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